Glomus Jugulare Tumour successfully treated with cyberknife

MEDICAL REPORT

This 41 years old gentleman a case of glomus jugulare tumour was diagnosed in 2005. He underwent embolisation in 15.03.2005 followed by excision of tumour on 18.03.2005 at Kerala.
On follow up in 5.05.2005 MRI showed residual lesion of size 3.4 x2.2 cm. Patient underwent SRS on 26.07.2005 for a dose of 10 Gy to 80% isodose at elsewhere.
On follow up found recurrence in 2007 for which he went to same center where no further treatment was offered.
Then he went to another hospital in Kerala where he was offered 2nd open surgery for which patient was not willing. Then in April 2010 MRI done showed increase in lesion size about 4.3 cm x 4.21 cm x6.0 cm in size.
TREATMENT

Patient came to Apollo speciality bospital for further treatment. Patient was treated with Cyberknife boost and IMRT after discussion through our tumour board
Now follow MRI revealed good regression of size of tumour and volume analysis showed almost close to 40 to 50 % of reduction in tumour volume.

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INDICATIONS FOR CYBERKNIFE TREATMENT

The indications for which cyberknife treatment could be useful is indicated below : Dr.Rathna devi, Senior consultant, Radiation oncology
Intra Cranial Tumours – Indications

• Skull base Tumours
• Meningiomas
• Brain Metastases
• Acoustic Schwannoma
• AVM
• Pituitary adenoma
• Low/Hi grade Glioma
Boost Re- irradiation
• Functional
• Trigeminal Neuralgia
• Spinal Tumors - Primary
Re irradiation - Metastases
• Craniophrangioma
• Chordoma
• Hamartoma
• Harmangio blastoma
• Glomus Jugular Tumor
• Boost for Nasopharynx carcinoma

EXTRA CRANIAL SITES – INDICATIONS
. Lung - Primary
- Metastases
• Liver - Primary
- Metastases
• Head & Neck - Tonsil
(Re Irradiation) - Larynx
- Pharynx
- Lacrimal Gland

• Sino Nasal Carcinoma - Boost
- Re –irradiation
• Carcinoma Pancreas
• Carcinoma Gall Bladder
• Para arotic lymph nodes
• Melanoma
• Carcinoma prostate
• Recurrent Orbital Tumours Renal Tumours
• Soft tissue sarcoma


To find out if a particular condition qualifies for cyberknife treatment you may please blog your comments or send in your query to lakshmipriya_b@apollohospitals.com

Stereotactic body radiotherapy for low-risk prostrate cancer

Stereotactic body radiotherapy for
low-risk prostate cancer:
five-year outcomes
Debra E. Freeman1 and Christopher R. King2
1 Naples Radiation Oncology, PA, USA
2 Department of Radiation Oncology, UCLA School of Medicine, CA, USA
Radiation Oncology 2011, 6:3doi:10.1186/1748-717X-6-3
Purpose
Hypofractionated, stereotactic body radiotherapy (SBRT) is an emerging treatment approach for prostate cancer. We present the outcomes for low-risk prostate cancer patients with a median follow-up of 5 years after SBRT.
Method and Materials
Between Dec. 2003 and Dec. 2005, a pooled cohort of 41 consecutive patients from Stanford, CA and Naples, FL received SBRT with CyberKnife for clinically localized, low-risk prostate cancer. Prescribed dose was 35-36.25 Gy in five fractions. No patient received hormone therapy. Kaplan-Meier biochemical progression-free survival (defined using the Phoenix method) and RTOG toxicity outcomes were assessed.
Results
At a median follow-up of 5 years, the biochemical progression-free survival was 93% (95% CI = 84.7% to 100%). Acute side effects resolved within 1-3 months of treatment completion. There were no grade 4 toxicities. No late grade 3 rectal toxicity occurred, and only one late grade 3 genitourinary toxicity occurred following repeated
urologic instrumentation.
Conclusion
Five-year results of SBRT for localized prostate cancer demonstrate the efficacy and safety of shorter courses of high dose per fraction radiation delivered with SBRT technique. Ongoing clinical trials are underway to further explore this treatment approach.

Source: www.accuray.com

For moreinformation you may blog your comments or write to lakshmipriya_b@apollohospitals.com