Successful CyberKnife Irradiation of 1000 cc
Hemicranial Meningioma: 6-year Follow-up
Meningiomas
are common benign tumors with accepted treatment approaches and usually don't
challenge healthcare specialists. We present a case of a huge unresectable
hemicranial meningioma, which was successfully treated with hypofractionated
irradiation.
A male
patient, sixty-two years of age, suffered for over 12 years from headaches,
facial deformity, right eye displacement, right eye movement restriction,
right-sided ptosis, and facial hypoesthesia. MRI and CT studies revealed an
extended hemicranial meningioma. Prior to irradiation, the patient underwent
four operations. Eventually, the tumor was irradiated with the CyberKnife in
August 2009. Tumor volume composed 1085 cc. The mean dose of 35.3 Gy was
delivered in 7 fractions (31.5 Gy at 72% isodose line comprising 95% of tumor
volume). The patient was followed during six years and experienced only mild
(Grade 1-2 CTCAE) acute skin and mucosa reactions. During the follow-up
period, we observed target volume shrinkage for 17% (for 26% after excluding
hyperostosis) and regression of intracranial hypertension signs.
We regard this clinical situation not as a
treatment recommendation, but as a demonstration of the underestimated
possibilities of hypofractionation regimen and CyberKnife system, both of which
are limited with our habit of conventional treatments.
Source : Scoop it
To know more about cyberknife kindly blog your comments or you can write to me at lakshmipriya_b@apollohospitals.com or call 9940675877
To know more about cyberknife kindly blog your comments or you can write to me at lakshmipriya_b@apollohospitals.com or call 9940675877
